- Oncology
- Inflammatory Bowel Disease
- Oncology Supportive Care (Mucositis)
- Dermatology
- Histology and Molecular Services
More Information
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Inflammatory Bowel Disease Models
Epistem’s IBD preclinical platform is an integrated offering combining a comprehensive range of models with a high level of IBD expertise. Epistem has a track record of delivering high quality preclinical results across a wide range of pharmaceutical clients.
Established models
- DSS
- TNBS
- IL-10
- Combination Studies (synergistic response in combination with current gold standards)
Currently extending Epistem's range of models to include:
- Chronic DSS
- T-cell transfer (in development)
- Oxazalone (in development)
Typical parameters measured:
- Weight
- Diarrhoea severity, faecal blood and overt rectal bleeding
- Colon weight/length
- Colitis severity score (histological)
- Extensive histometric severity score
- Myeloperoxidase assay
- Gene expression analysis
- Immunohistochemistry
Example IBD Data












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