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Laser Capture Microdissection

Laser Capture Microdissection (LCM) - A Strategy for Success

Micro-sampling by laser capture microdissection is a powerful tool allowing specific analysis from whole tissues, in heterogeneous microenvironments such as tumours, where less well represented target cells are dwarfed by tissue stroma and other cell types. Whilst the application is potentially powerful for target discovery and mechanistic understanding, the process is notoriously difficult, particularly in clinical specimens. Our Laser Capture Microdissection team has evaluated the findings from all the studies run in our GCLP-accredited labs and devised a strategy for LCM studies maximising the potential of success and giving the sponsor control over go/no go decisions.