In Vitro Cytotoxicity

Epistem provides a range of standard in vitro cytotoxicity assays. These assays can be carried out on a wide range of human tumour cell lines, many of which have also been validated in subcutaneous xenografts.

Readouts

  • IC50 and EC50 doses
  • Viable cell number, proliferation and apoptosis
  • FACS analysis of target expression
  • Gene expression analysis of target effects

Image generated using the Acumen Explorer(R) showing a reduction of confluence of HCT 116 cells observed in a cytotoxicity assay

Image generated using the Acumen Explorer® showing a reduction of confluence of HCT 116 cells observed in a cytotoxicity assay

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In Vitro Cytotoxicity Assays?

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+44 (0)161 850 7600

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