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Cancer Stem Cells

Epistem offers tumour sphere assays as part of a comprehensive preclinical oncology programme, from initial assessment of target gene or protein expression to evaluation of cancer stem cell targeting efficacy in vitro.


In Vitro and In Vivo Human Angiogenesis Assays

Epithelial Tumour Xenograft Services

Epistem provides specialist subcutaneous xenografting services covering a comprehensive range of in vivo epithelial tumour models. Specialist radiation and chemotherapy combination models, and complementary assessment of target and biomarker ...

In Vivo Orthotopic Models of Patient-Derived (PDX) and Cell Line Based Leukemia

Epistem provides clinically relevant in vivo models of leukemia using both patient-derived material and established cell line models. Luciferase imaging enables early detection of leukemia, allowing for an extended treatment window and longitudinal mo

Orthotopic and Metastatic Cancer
In Vivo Orthotopic Models
for More Accurate Representation of Clinical Disease

Epistem provides clinically relevant orthotopic in vivo models of solid and metastatic tumors, using highly sensitive state-of-the-art optical imaging with luc+ cell lines, enabling real time visualization of therapeutic outcomes.