Epistem Limited

disease & therapeutic research models

Inflammatory Bowel Disease

GI Toxicity and Mucositis

Immune Cell Assays

Rheumatoid Arthritis

services

Gene Expression Analysis

Histology and IHC Services

Laser Capture Microdissection

Analytical Services

Plucked Hair Analysis

Spotlight On...

Measuring intratumoral vessel density using automated image analysis
Digital image analysis to analyse the intratumoral vessel density within specified regions of resected colon and TMA sections of colon…
The importance of Reg4 in the response of the colonic epithelium to inflammation
Upregulation of, or treatment with Reg4 was associated with the maintenance and proliferation of colonic organoid cultures, the epithelial response…
Human 3D Gastrointestinal Microtissue Barrier Function As a Predictor of …
New preclinical approaches are required for earlier testing of therapies for GI-toxicity. In this study the authors describe an in vitro human 3D GI…
Identification of a Radiosensitivity Molecular Signature Induced by …
Androgen Deprivation Therapy (ADT) has demonstrated improved clinical success with further anti-tumour efficacy when combined with XRT, however, half…
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and …
Prophylactic TNF blockade may safely allow doses of ipilimumab to be increased in immune checkpoint blockade combined…

Announcements

NEWS: Epistem licence Hubrecht Organoid Technology to expand preclinical toxicology service portfolio
2019-07-15
Epistem Limited has announced the expansion of its in vitro model portfolio by the completion of an agreement with Hubrecht Organoid Technology (HUB)…
NEWS: Epistem completes board line up and launches new NGS service
2018-11-28
Epistem Limited, the Manchester based pre-clinical and clinical research services company announces the completion of its Board appointments.…
NEWS: 10 Years GCLP Accreditation at Epistem
2019-01-11
We are pleased to announce the successful GCLP re-accreditation of our laboratories.

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