Epistem Limited

disease & therapeutic research models

Inflammatory Bowel Disease

GI Toxicity and Mucositis

Immune Cell Assays

Rheumatoid Arthritis

services

Gene Expression Analysis

Histology and IHC Services

Laser Capture Microdissection

Analytical Services

Plucked Hair Analysis

Spotlight On...

A murine platform to evaluate therapies against radiation-induced …
Models to service radiation-induced gastrointestinal syndrome are limited, this study shows a platform to study genes linked to intestinal radiation…
Plucked hair follicles from patients with Chronic Discoid Lupus Erythematosus …
This pilot study showed that a disease-specific gene signature for Chronic Discoid Lupus Erythematosus can be obtained from plucked hair follicles…
In vivo selection reveals autophagy promotes adaptation of metastatic …
An increase in autophagic potency among ovarian cancer cells may be crucial for selection of metastatic colonies in the abdominal microenvironment.…
Derivation of adult canine intestinal organoids for translational research in …
This study describes the development and long-term maintenance of small intestine and colon in vitro canine organoids using whole tissue and biopsy…
Spatial metagenomic characterisation of microbial biogeography in the gut
Evaluation of a novel technique, MaPS-seq, a multiplexed protocol combining the positive aspects of metagenomics, transcriptomics and imaging to…

Announcements

NEWS: Epistem licence Hubrecht Organoid Technology to expand preclinical toxicology service portfolio
2019-07-15
Epistem Limited has announced the expansion of its in vitro model portfolio by the completion of an agreement with Hubrecht Organoid Technology (HUB)…
NEWS: Epistem completes board line up and launches new NGS service
2018-11-28
Epistem Limited, the Manchester based pre-clinical and clinical research services company announces the completion of its Board appointments.…
NEWS: 10 Years GCLP Accreditation at Epistem
2019-01-11
We are pleased to announce the successful GCLP re-accreditation of our laboratories.

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