Angiogenesis
In Vitro and In Vivo Human Angiogenesis Assays
In Vitro and In Vivo Human Angiogenesis Assays
Cancer Stem Cells
In Vitro Assay to Assess Cancer Stem Cell Targeting Agents
Epistem offers tumour sphere assays as part of a comprehensive preclinical oncology programme, from initial assessment of target gene or protein expression to evaluation of cancer stem cell targeting efficacy in vitro.
Leukemia
In Vivo Orthotopic Models of Patient-Derived (PDX) and Cell Line Based Leukemia
Epistem provides clinically relevant in vivo models of
leukemia using both patient-derived material and established
cell line models. Luciferase imaging enables early detection
of leukemia, allowing for an extended treatment window and
longitudinal mo
Orthotopic and Metastatic Cancer
In Vivo Orthotopic Models for More Accurate Representation of Clinical Disease
Epistem provides clinically relevant orthotopic in vivo models
of solid and metastatic tumors, using highly sensitive
state-of-the-art optical imaging with luc+ cell lines, enabling
real time visualization of therapeutic outcomes.
Xenografting
Epithelial Tumour Xenograft Services
Epistem provides specialist subcutaneous xenografting
services covering a comprehensive range of in vivo epithelial
tumour models.
Specialist radiation and chemotherapy combination models,
and complementary assessment of target and biomarker
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