Why is my email required?
tick this box if you would like to be added to our mailing list.
Epistem provides laboratory GCLP (microarray and qPCR)
and point of care (Genedrive
Epistem provides specialist epithelial tissue and stem cell
analysis to investigate the aetiology, mechanism and
prevention of epithelial toxicity.
High quality preclinical data from a range of in vivo IBD
models and target validation studies to aid the development
of new anti-inflammatory therapies.
In Vitro and In Vivo Human Angiogenesis Assays
Epistem provides clinically relevant in vivo models of
leukemia using both patient-derived material and established
cell line models. Luciferase imaging enables early detection
of leukemia, allowing for an extended treatment window and
Epistem provides a range of in vitro and in vivo models to
assess the complex processes involved in wound healing
and to determine the effect of agents on healing rate.
We have developed a reproducible, well growing and robust subcutaneous model of LNCaP with an effective response to both conventional standard of care (SOC) chemotherapy such as docetaxel and the non-steroidal androgen receptor inhibitor bicalutamide (Casodex).
Ex vivo plucked hair assessment generated a dose-dependent and biologically relevant transcriptional signature following exposure to BEZ235, and substantiate that plucked anagen scalp hair is an ideal non-invasive surrogate tissue to obtain drug-induced pharmacodynamic biomarker and target engagement information from oncology patients.
Gene Expression Analysis
GI Toxicity and Mucositis
Histology and IHC Services
Inflammatory Bowel Disease
Laser Capture Microdissection
Plucked Hair Analysis
All global categories
View all downloads
© 2013, 2020 Epistem Ltd.
Call us on +44 (0)161 850 7600 or email firstname.lastname@example.org
Accelerating Drug Development with Innovative Services
Don't show this again