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brochure listing

Plucked Hair Analysis

Plucked Hair Biomarker Platform
Gene and Protein Expression in Single Scalp Hairs

Epistem provides a unique plucked hair biomarker platform to drug development companies targeting intracellular signalling pathways in oncology and other therapeutic areas. Plucked hair analysis offers a simple to apply and minimally invasive techniqu

Plucked Hair Biomarker Analysis
Reproducible Gene Expression Profiles from Plucked Hair

Plucked hair is an attractive non-invasive surrogate tissue to aid drug development programs, particularly with respect to phamacodynamic biomarker discovery and clinical applications. With low intra- and inter-donor variation key to successful utility

Epithelial Tumour Xenograft Services

Epistem provides specialist subcutaneous xenografting services covering a comprehensive range of in vivo epithelial tumour models. Specialist radiation and chemotherapy combination models, and complementary assessment of target and biomarker ...

poster listing

Plucked Hair Analysis

Plucked Anagen Scalp Hair
A comparison between different analytical techniques

Ex vivo plucked hair assessment generated a dose-dependent and biologically relevant transcriptional signature following exposure to BEZ235, and substantiate that plucked anagen scalp hair is an ideal non-invasive surrogate tissue to obtain drug-induced pharmacodynamic biomarker and target engagement information from oncology patients.