Epistem provides a suite of analytical services which can be utilised as an integrated component of an in-house study package or as a stand-alone service.
Epistem has been providing analytical support to drug discovery and development pipelines for over ten years. World-renowned expertise in epithelial stem cell biology, specifically in the gastrointestinal epithelium, skin and hair, forms the basis of Epistem's analytical services. This knowledge has been applied to provide exceptional support for Epistem's portfolio of preclinical models and a flexible, high quality solution for contract sample analysis.
Epistem proudly offers a GCLP accredited histology and immunohistochemistry service at a central facility in Manchester, UK. Delivered by a team of experienced histologists, reliable, quality controlled slides and data can be provided for any histological requirement. Associated image capture and morphological quantification can also be provided using the Aperio® ScanScope® digital slide scanner. High quality, publication-ready images with high throughput automated quantitative analysis can be produced with GCLP compliant image archiving and analysis.
The first in the UK, Epistem’s facilities include the Bruker In Vivo Xtreme Imaging System. Combined with established expertise in imaging, this sophisticated, high resolution, multi-modal system is a powerful addition to Epistem’s in vivo preclinical models. Sensitive high throughput analysis of cell phenotypes by FACS, and proteins and cytokines by multiplex, is also provided in support of Epistem's models and assays and as a sample analysis service.
Epistem's gene expression service is a powerful tool providing highly sensitive, GCLP compliant sample analysis. This service specialises in providing robust and reliable gene expression information from very small amounts of starting material.