B and T Cell Receptor Sequencing Services

Epistem provides B-cell receptor (BCR) and T-cell receptor (TCR) characterisation services using NGS to provide a comprehensive assessment of COVID-19 vaccines.

Our sequencing service provides vital information including:

  • Ascertaining if COVID-19 vaccines induced a specific change in the TCR and BCR repertoires. 
  • High-throughput sequencing (HTS) to help clarify the immune response to the COVID-19 vaccine. 
  • Determine if COVID-19 vaccines induce COVID-19 antigen-specific T cells and B cells, and that, concomitantly, the TCR β and BCR IgG H chain CDR3 repertoires change significantly in response to antigenic stimuli. 
  • Epistem can separate cell populations and perform single cell sequencing (using the 10x Genomics platform) or alternatively assess separated cell populations.


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COVID-19 Vaccination Assessments?

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+44 (0)161 850 7600