B and T Cell Receptor Sequencing Services
Epistem provides B-cell receptor (BCR) and T-cell receptor (TCR) characterisation services using NGS to provide a comprehensive assessment of COVID-19 vaccines.
Our sequencing service provides vital information including:
- Ascertaining if COVID-19 vaccines induced a specific change in the TCR and BCR repertoires.
- High-throughput sequencing (HTS) to help clarify the immune response to the COVID-19 vaccine.
- Determine if COVID-19 vaccines induce COVID-19 antigen-specific T cells and B cells, and that, concomitantly, the TCR β and BCR IgG H chain CDR3 repertoires change significantly in response to antigenic stimuli.
- Epistem can separate cell populations and perform single cell sequencing (using the 10x Genomics platform) or alternatively assess separated cell populations.