Imaging

Epistem’s facilities include the first Bruker In Vivo Xtreme Imaging System in the UK. The high resolution imaging system combines four modalities; luminescence, fluorescence, radioisotope imaging and X-ray. This sophisticated system enables high throughput, flexible imaging with rapid multimodal acquisition and is specifically designed for complex preclinical investigations. Combined with established expertise in imaging, this state-of-the-art system is a powerful addition to Epistem’s in vivo preclinical models. 

Capabilities of Epistem’s Imaging Service: 

• Non-invasive longitudinal tumour xenograft imaging
• Stem cell tracking
• Imaging of inflammation
• Tracking and validating single or multimodal nanoparticles 
• Imaging and validating new probes and biomarkers
• Non-invasively image changes in signalling cascades
• Discover how genetics, small molecules and therapeutics affect biochemical pathways
• Quantify changes in bone and soft tissue phenotype
• High throughput pharmacodynamic studies

Epistem's imaging service can be used to support in-house models including:

Oncology

• Orthotopic Models

Inflammation

• Inflammatory bowel disease
• Collagen-induced arthritis